Overview

Zonefight-1gm (Ceftriaxone 1 gm) Injection is a broad-spectrum third-generation cephalosporin antibiotic used to treat a wide variety of bacterial infections. It is administered via intravenous (IV) or intramuscular (IM) injection.

✅ Uses of Ceftriaxone 1 gm Injection:

Ceftriaxone is used to treat the following conditions:

1. Respiratory Tract Infections – e.g., pneumonia, bronchitis

2. Urinary Tract Infections (UTIs)

3. Skin and Soft Tissue Infections

4. Bone and Joint Infections

5. Intra-abdominal Infections – including peritonitis

6. Septicemia (blood infections)

7. Meningitis – bacterial infections of the brain/spinal cord

8. Gonorrhea – a sexually transmitted infection

9. Pelvic Inflammatory Disease (PID)

10. Prophylaxis Before Surgery – to prevent infections

11. Ear, Nose, and Throat Infections – e.g., otitis media, sinusitis

💊 Benefits of Ceftriaxone 1 gm Injection:

1. Broad-spectrum activity – Effective against both Gram-positive and Gram-negative bacteria.

2. Long half-life – Once-daily dosing is usually sufficient.

3. Potent bactericidal action – Kills bacteria by inhibiting cell wall synthesis.

4. Effective in severe infections – Used in hospitals for serious infections like sepsis and meningitis.

5. Stable against beta-lactamases – Resists degradation by many bacterial enzymes.

6. Good tissue penetration – Reaches therapeutic levels in CSF, bones, and lungs.

7. Convenient IM/IV use – Useful in both hospital and outpatient settings.

⚠️ Precautions and Side Effects:

• Common side effects: Pain at injection site, diarrhea, rash, nausea.

• Serious (rare): Allergic reactions, gallbladder sludge, superinfections.

• Not for use in neonates with calcium-containing IV solutions – due to risk of precipitates.